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Index > Protein center > NEFM(Gene name) > Human
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  • NEFM (Gene name),
  • Neurofilament medium polypeptide (Protein name ),  NFM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NEFM(NEF3;NFM);
    Protein name:
    Neurofilament medium polypeptide(NF-M);
    Alternative:
    Neurofilament 3;160 kDa neurofilament protein;Neurofilament triplet M protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    916
    Sequence:
    50:
    MSYTLDSLGN | PSAYRRVTET | RSSFSRVSGS | PSSGFRSQSW | SRGSPSTVSS | 
    100:
    SYKRSMLAPR | LAYSSAMLSS | AESSLDFSQS | SSLLNGGSGP | GGDYKLSRSN | 
    150:
    EKEQLQGLND | RFAGYIEKVH | YLEQQNKEIE | AEIQALRQKQ | ASHAQLGDAY | 
    200:
    DQEIRELRAT | LEMVNHEKAQ | VQLDSDHLEE | DIHRLKERFE | EEARLRDDTE | 
    250:
    AAIRALRKDI | EEASLVKVEL | DKKVQSLQDE | VAFLRSNHEE | EVADLLAQIQ | 
    300:
    ASHITVERKD | YLKTDISTAL | KEIRSQLESH | SDQNMHQAEE | WFKCRYAKLT | 
    350:
    EAAEQNKEAI | RSAKEEIAEY | RRQLQSKSIE | LESVRGTKES | LERQLSDIEE | 
    400:
    RHNHDLSSYQ | DTIQQLENEL | RGTKWEMARH | LREYQDLLNV | KMALDIEIAA | 
    450:
    YRKLLEGEET | RFSTFAGSIT | GPLYTHRPPI | TISSKIQKPK | VEAPKLKVQH | 
    500:
    KFVEEIIEET | KVEDEKSEME | EALTAITEEL | AVSMKEEKKE | AAEEKEEEPE | 
    550:
    AEEEEVAAKK | SPVKATAPEV | KEEEGEKEEE | EGQEEEEEED | EGAKSDQAEE | 
    600:
    GGSEKEGSSE | KEEGEQEEGE | TEAEAEGEEA | EAKEEKKVEE | KSEEVATKEE | 
    650:
    LVADAKVEKP | EKAKSPVPKS | PVEEKGKSPV | PKSPVEEKGK | SPVPKSPVEE | 
    700:
    KGKSPVPKSP | VEEKGKSPVS | KSPVEEKAKS | PVPKSPVEEA | KSKAEVGKGE | 
    750:
    QKEEEEKEVK | EAPKEEKVEK | KEEKPKDVPE | KKKAESPVKE | EAVAEVVTIT | 
    800:
    KSVKVHLEKE | TKEEGKPLQQ | EKEKEKAGGE | GGSEEEGSDK | GAKGSRKEDI | 
    850:
    AVNGEVEGKE | EVEQETKEKG | SGREEEKGVV | TNGLDLSPAD | EKKGGDKSEE | 
    900:
    KVVVTKTVEK | ITSEGGDGAT | KYITKSVTVT | QKVEEHEETF | EEKLVSTKKV | 
    916:
    EKVTSHAIVK | EVTQSD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human NF-M
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    ELISA Kit for Human NF-M
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    ELISA Kit for Human NF-M
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    ELISA Kit for Human NF-M
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    ELISA Kit for Human NF-M
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    MSDS:
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    ELISA Kit for Human NF-M
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    E5025r
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    MSDS:
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    ELISA Kit for Human NF-M
    Cat.:
    E5025b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NF-M
    Cat.:
    U5025b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NF-M
    Cat.:
    U5025r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NF-M
    Cat.:
    U5025m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NF-M
    Cat.:
    U5025p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NF-M
    Cat.:
    U5025h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human NF-M
    MSDS:
    Please sign in first.
    CLIA Kit for Human NF-M
    MSDS:
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    Polyclonal Antibody for Human NF-M
    Polyclonal Antibody for Human NF-M
    Cat.:
    P5025Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NF-M
    Polyclonal Antibody for Human NF-M
    Polyclonal Antibody for Human NF-M
    Cat.:
    P5025Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NF-M
    Polyclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Monoclonal Antibody for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M
    Protein for Human NF-M

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    References
    1. 1.
      "The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family."
      Myers M.W. , Lazzarini R.A. , Lee V.M.-Y. , Schlaepfer W.W. , Nelson D.L.
      EMBO J.6:1617-1626(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-439
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-439
      tissue: Retina.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT THR-439
      tissue: Brain.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT THR-439
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-439
      tissue: Brain.
    6. 7.
      "Identification of the major multiphosphorylation site in mammalian neurofilaments."
      Lee V.M.-Y. , Otvos L. Jr. , Carden M.J. , Hollosi M. , Dietzschold B. , Lazzarini R.A.
      Proc. Natl. Acad. Sci. U.S.A.85:1998-2002(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
    7. 8.
      Lubec G. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 128-137; 140-155; 169-184 AND 592-606;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Fetal brain cortex.
    8. 9.
      "PKN associates and phosphorylates the head-rod domain of neurofilament protein."
      Mukai H. , Toshimori M. , Shibata H. , Kitagawa M. , Shimakawa M. , Miyahara M. , Sunakawa H. , Ono Y.
      J. Biol. Chem.271:9816-9822(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY PKN1
    9. 10.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-837;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] THR-439;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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